Bloomberg News " Frequent Boosters Spur Warning on Immune Response"
Frequent Boosters Spur Warning on Immune Response
ByIrina Anghel

January 11, 2022

European Union regulators warned that frequent Covid-19 booster shots could adversely affect the immune response and may not be feasible.  

Repeat booster doses every four months could eventually weaken the immune response and tire out people, according to the European Medicines Agency. Instead, countries should leave more time between booster programs and tie them to the onset of the cold season in each hemisphere, following the blueprint set out by influenza vaccination strategies, the agency said. 

The advice comes as some countries consider the possibility of offering people second booster shots in a bid to provide further protection against surging omicron infections. Earlier this month Israel became the first nation to start administering a second booster, or fourth shot, to those over 60. The U.K. has said that boosters are providing good levels of protection and there is no need for a second booster shot at the moment, but will review data as it evolves. 

Boosters “can be done once, or maybe twice, but it’s not something that we can think should be repeated constantly,” Marco Cavaleri, the EMA head of biological health threats and vaccines strategy, said at a press briefing on Tuesday. “We need to think about how we can transition from the current pandemic setting to a more endemic setting.”

The EU regulator also said at the briefing that oral and intravenous antivirals, such as Paxlovid and Remdesivir, maintain their efficacy against omicron. The agency said that April is the soonest it could approve a new vaccine targeting a specific variant, as the process  takes about three to four months. Some of the world’s largest vaccine-makers have said they are looking at producing vaccines that could target new variants. 

— With assistance by April Roach

This follows on from the death of E.U. Parliament head David Sassoli who very recently died of "Immune Complication" on the same day as the report above was published.

EU Parliament Head David Sassoli Dies of Immune Complication

David Sassoli, the president of the European Parliament, died early Tuesday following an immune complication, according to his spokesman.

Sassoli, who was 65, had been under care in Aviano, Italy, Robert Cuillo, his spokesman, said on Twitter. He had been hospitalized since Dec. 26 due to a “serious complication due to a dysfunction of the immune system,” according to a statement released on Monday.
The Italian Socialist was chosen in 2019 to lead the European legislature in a deal that also saw Ursula von der Leyen tapped to become European Commission President.
Sassoli was a former journalist and decade-long veteran of the EU Parliament.

“David Sassoli was a passionate journalist, an extraordinary President of the European Parliament and above all a dear friend,” von der Leyen wrote on Twitter after the announcement. 

Lawmakers are due to elect a new president Jan. 18. 
During his stint at the parliament, Sassoli led on the European railway reform and the Single European Sky as a member of the Committee for Transport and Tourism.
In an address to EU leaders last month, Sassoli said that Europe needs most of all “a new project of hope,” through innovation in all areas, protection of Europeans and its democratic model.

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Bloomberg News " Frequent Boosters Spur Warning on Immune Response" - by Sed libera nos - 01-13-2022, 03:08 AM

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